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Sigma-Aldrich

4-(Trifluoromethyl)phenylhydrazine

96%

Synonym(s):

1-(4-Trifluoromethylphenyl)hydrazine, 4-Trifluoromethylphenylhydrazine, [4-(Trifluoromethyl)phenyl]hydrazine, p-Trifluoromethylphenylhydrazine

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About This Item

Linear Formula:
CF3C6H4NHNH2
CAS Number:
368-90-1
Molecular Weight:
176.14
MDL number:
MFCD00042508
UNSPSC Code:
12352100
PubChem Substance ID:
24865801
NACRES:
NA.22

Assay

96%

bp

118-122 °C/17 mmHg (lit.)

mp

63-65 °C (lit.)

storage temp.

2-8°C

SMILES string

NNc1ccc(cc1)C(F)(F)F

InChI

1S/C7H7F3N2/c8-7(9,10)5-1-3-6(12-11)4-2-5/h1-4,12H,11H2

InChI key

DBNLGTYGKCMLLR-UHFFFAOYSA-N

General description

4-(Trifluoromethyl)phenylhydrazine participates as phenylhydrazine-based reductant containing fluorine atoms in the one-step reduction and functionalization of graphene oxide.

Application

4-(Trifluoromethyl)phenylhydrazine may be used for the synthesis of 2-iodo-9-trifluoromethyl-paullone.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C Kunick et al.
Bioorganic & medicinal chemistry letters, 10(6), 567-569 (2000-03-31)
9-Trifluoromethyl-paullones with a carbon chain in the 2-position were synthesized by palladium-catalyzed coupling reactions of a 2-iodoprecursor with terminal alkenes or alkynes, respectively. The introduction of a 2-cyanoethyl substituent led to a significant enhancement of CDK1/cyclin B inhibiting property and
Su-Hyeon Kim et al.
Nanoscale, 6(13), 7183-7187 (2014-05-08)
A one-step reduction and functionalization of graphene oxide (FrGO) was easily achieved using a novel phenylhydrazine-based reductant containing fluorine atoms, which can induce p-type doping due to its high electronegativity. The FrGO-based OPV exhibited a high power conversion efficiency of

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