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Sigma-Aldrich

Brij® S10

average Mn ~711

Synonym(s):

Polyethylene glycol octadecyl ether, Polyoxyethylene (10) stearyl ether

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About This Item

Linear Formula:
C18H37(OCH2CH2)nOH, n~10
CAS Number:
9005-00-9
MDL number:
MFCD00074177
UNSPSC Code:
12162002
PubChem Substance ID:
24864250
NACRES:
NA.23

mol wt

average Mn ~711

mp

37-39 °C (lit.)

density

0.964 g/mL at 25 °C (lit.)

HLB

12

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChI key

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

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Legal Information

Brij is a registered trademark of Croda International PLC

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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USP

USP

1547368

Polyoxyl 20 stearyl ether

Sigma-Aldrich

Sigma-Aldrich

421359

MERPOL® SH surfactant

S Rahima Benhabbour et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 63-71 (2011-11-01)
Lipid-based oil-filled nanoparticles (NPs) with a high concentration of surface-chelated nickel (Ni-NPs) were successfully prepared using a Brij 78-NTA-Ni conjugate synthesized with Brij 78 (Polyoxyethylene (20) stearyl ether) and nitrilotriacetic acid (NTA). The facile incorporation of the Brij 78-NTA-Ni conjugate
M Fukahori et al.
Chemical & pharmaceutical bulletin, 44(12), 2335-2337 (1996-12-01)
The effects of the structures of non-ionic surfactants on the uptake of butyl p-hydroxybenzoate (BP) into Escherichia coli cells and its antibacterial activity were systematically studied using polyoxyethylene alkyl ethers (PAEs) possessing various oxyethylene and hydrocarbon chain lengths. The uptake
Jigna D Patel et al.
Pharmaceutical research, 24(2), 343-352 (2006-12-21)
The purpose of these studies was to prepare nanoparticles (NPs) with a small amount of surface-chelated nickel for obtaining enhanced binding of histidine-tagged (his-tag) proteins compared to non-histidine-tagged protein binding to charged nanoparticles. NPs were prepared from oil-in-water microemulsion precursors
Tatsuaki Tagami et al.
Journal of controlled release : official journal of the Controlled Release Society, 152(2), 303-309 (2011-02-23)
We have developed a novel and simplified thermosensitive liposomal formulation (HaT: Hyperthermia-activated cytoToxic) composed of DPPC lipid and Brij78 (96:4, molar ratio). The HaT nanoparticles were loaded with doxorubicin (DOX) with >95% efficiency when a pH gradient method and a
Joanna M Koziara et al.
Journal of controlled release : official journal of the Controlled Release Society, 99(2), 259-269 (2004-09-24)
Despite the advances in tumor therapy, patients with primary brain tumors and brain metastases have a very poor prognosis. Low responses to chemotherapy are mainly attributed to impermeability of the blood-brain barrier to cytotoxic agents. Paclitaxel has been shown to
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