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PHL89281

Silychristin

phyproof® Reference Substance

Synonym(e):

Silymarin II

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About This Item

Empirische Formel (Hill-System):
C25H22O10
CAS-Nummer:
33889-69-9
Molekulargewicht:
482.44
MDL-Nummer:
MFCD00883715
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

primary reference standard

Produktlinie

phyproof® Reference Substance

Assay

≥95.0% (HPLC)

Hersteller/Markenname

PhytoLab

Anwendung(en)

food and beverages

Format

neat

Lagertemp.

2-8°C

SMILES String

COc1cc(ccc1O)[C@@H]2Oc3c(O)cc(cc3[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O

InChI

1S/C25H22O10/c1-33-18-6-10(2-3-15(18)28)23-14(9-26)13-4-11(5-17(30)25(13)35-23)24-22(32)21(31)20-16(29)7-12(27)8-19(20)34-24/h2-8,14,22-24,26-30,32H,9H2,1H3/t14-,22+,23+,24-/m1/s1

InChIKey

BMLIIPOXVWESJG-LMBCONBSSA-N

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Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Anwendung


  • Unveiling the healing properties of 2,3-dehydrosilychristin: A silymarin-derived flavonolignan with potent pharmacological activities, highlighting its significance in mitigating oxidative stress and enhancing cellular repair mechanisms in liver tissues (Tripathi et al., 2024).

  • Application of SNAP-tag-EGFR cell membrane chromatography model: This study identifies Silychristin as a key antitumor agent in Silybum marianum, detailing its role in targeted cancer therapies and its efficacy in inhibiting tumor cell proliferation (Zhang et al., 2024).

  • Pharmaceutical prospects of Silymarin for neurological patients: Provides an update on the neuroprotective properties of Silychristin, emphasizing its therapeutic potential in treating neurological disorders through modulation of oxidative stress and inflammation (Ranjan and Gautam, 2023).

  • Structural basis of Nrf2 activation by flavonolignans: Explores how Silychristin, as part of the Silymarin complex, activates the Nrf2 pathway, offering insights into its application in enhancing antioxidant responses at the molecular level (Bello, 2023).

  • Mechanistic Insights into the Pharmacological Significance of Silymarin: Reviews the broad pharmacological actions of Silychristin within the Silymarin complex, discussing its anti-inflammatory, antioxidant, and antifibrotic roles, which are pivotal for comprehensive healthcare applications (Wadhwa et al., 2022).

Sonstige Hinweise

This compound is commonly found in plants of the genus: silybum

Rechtliche Hinweise

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number
124419085
112983074
16046
101980944

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