U6758

UCL 2077

≥98% (HPLC), solid

• Synonym(e): (3-Triphenylmethylaminomethyl)pyridine
• Empirische Formel (Hill-System): C₂₅H₂₂N₂
• CAS-Nummer: 918311-87-2
• Molekulargewicht: 350.46
• MDL-Nummer: MFCD00585879
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329827644
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Farbe: white
• Löslichkeit: DMSO: soluble >20 mg/mL; H₂O: insoluble
• SMILES String: C(NC(c1ccccc1)(c2ccccc2)c3ccccc3)c4cccnc4
• InChI: 1S/C25H22N2/c1-4-12-22(13-5-1)25(23-14-6-2-7-15-23,24-16-8-3-9-17-24)27-20-21-11-10-18-26-19-21/h1-19,27H,20H2
• InChIKey: PQFNWDHABGBCHB-UHFFFAOYSA-N

Beschreibung

Anwendung

UCL 2077 has been used for slow afterhyperpolarization (sAHP) studies in thalamic paraventricular nucleus (PVT) neurons. UCL 2077 has also been used for studying its effects on the increase in excitability of hippocampal pyramidal cells.

Biochem./physiol. Wirkung

UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker.

Angaben zur Herstellung

UCL 2077 is soluble in DMSO at a concentration >20 mg/ml and is insoluble in water.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves