U211130

DMT-2′O-Methyl-rU Phosphoramidit

configured for ABI

• Synonym(e): 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-uridin, 3′-[2-Cyanoethyl N,N-bis(1-methylethyl)phosphoramidit], DMT-2′O-Methyl-rU Amidit
• Empirische Formel (Hill-System): C₄₀H₄₉N₄O₉P
• CAS-Nummer: 110764-79-9
• Molekulargewicht: 760.81
• MDL-Nummer: MFCD00792626
• UNSPSC-Code: 41116105
• PubChem Substanz-ID: 329827607
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: non-animal source (no BSE/TSE risk)
• Produktlinie: Proligo Reagents
• Assay: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• Form: powder
• Methode(n): oligo synthesis: suitable
• Verunreinigungen: ≤0.1% single unspecified Impurity (reversed phase HPLC); ≤0.3% mU2 (reversed phase HPLC, Hydrolysate); ≤0.3% mU3 (reversed phase HPLC, DMT-rme); ≤0.3% water content (Karl Fischer); ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR); ≤1.0% mU1 (reversed phase HPLC, DMT-rUme-DMT); ≤3% residual Solvent content
• Farbe: white to off-white
• λ: conforms (UV/VIS Identity)
• Eignung: conforms to structure for H-NMR; conforms to structure for LC-MS
• Kompatibilität: configured for ABI
• Nukleosidprofil: base: uridine; base protecting group: none; 2' protecting group: methyl; 5' protecting group: DMT; deprotection: fast/standard
• Lagertemp.: 2-8°C
• SMILES String: CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1N5C=CC(=O)NC5=O
• InChI: 1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-36-34(52-38(37(36)49-7)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1
• InChIKey: UVUOJOLPNDCIHL-XKZJCBTISA-N

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable