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Merck

T1694

Sigma-Aldrich

(E)-4-Amino-2-butenoic acid

Synonym(e):

trans-4-Aminocrotonic acid, TACA

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About This Item

Empirische Formel (Hill-System):
C4H7NO2
CAS-Nummer:
Molekulargewicht:
101.10
MDL-Nummer:
UNSPSC-Code:
12352106
PubChem Substanz-ID:

Form

powder

Farbe

white

Löslichkeit

H2O: 10 mg/mL, clear

SMILES String

NC\C=C\C(O)=O

InChI

1S/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1+

InChIKey

FMKJUUQOYOHLTF-OWOJBTEDSA-N

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Kinga K Borowicz et al.
Pharmacological reports : PR, 57(1), 121-123 (2005-04-26)
In the present study, we evaluated TACA (a potent agonist of GABA(A) and GABA(C) receptors) in the electroconvulsive threshold test in mice. Surprisingly, TACA (at 15 and 25 mg/kg) significantly decreased the threshold. The highest ineffective dose of TACA was
D Zhang et al.
Trends in pharmacological sciences, 22(3), 121-132 (2001-03-10)
In less than a decade our knowledge of the GABA(C) receptor, a new type of Cl(-)-permeable ionotropic GABA receptor, has greatly increased based on studies of both native and recombinant receptors. Careful comparison of properties of native and recombinant receptors
Yan Lu et al.
American journal of physiology. Renal physiology, 308(9), F1020-F1025 (2015-01-23)
Adenosine plays an important role in regulation of renal microcirculation. All receptors of adenosine, A1, A2A, A2B, and A3, have been found in the kidney. However, little is known about the location and function of the A3 receptor in the
Seung Yun Yang et al.
Nature communications, 4, 1702-1702 (2013-04-18)
Achieving significant adhesion to soft tissues while minimizing tissue damage poses a considerable clinical challenge. Chemical-based adhesives require tissue-specific reactive chemistry, typically inducing a significant inflammatory response. Staples are fraught with limitations including high-localized tissue stress and increased risk of
Leonie M Kamminga et al.
PLoS genetics, 8(7), e1002702-e1002702 (2012-07-26)
RNA interference (RNAi)-related pathways affect gene activity by sequence-specific recruitment of Ago proteins to mRNA target molecules. The sequence specificity of this process stems from small RNA (sRNA) co-factors bound by the Ago protein. Stability of sRNA molecules in some

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