SRP8048

PEDF mouse

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• Synonym(e): Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3
• CAS-Nummer: 607410-75-3
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: mouse
• Rekombinant: expressed in CHO cells
• Markierung: FLAG^® tagged
• Assay: >95% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: ~47 kDa by SDS-PAGE
• Verpackung: pkg of 10 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Verunreinigungen: <0.01 EU/μg endotoxin, tested
• Farbe: white
• UniProt-Hinterlegungsnummer: P97298
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: mouse ... Serpinf1(20317)

Beschreibung

Allgemeine Beschreibung

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

Physikalische Form

Lyophilized from PBS.

Rekonstituierung

Reconstitute with 100 μL deionized water.

Sonstige Hinweise

Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG^®-tag.

Rechtliche Hinweise

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable