SRP8046

Netrin-1 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• Synonym(e): ACRP30headless:TNFSF13, NTN1
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in HEK 293 cells
• Assay: >95% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: ~90 kDa by SDS-PAGE
• Verpackung: pkg of 10 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Verunreinigungen: <0.1 EU/μg endotoxin, tested
• Farbe: white
• UniProt-Hinterlegungsnummer: O95631
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... NTN1(9423)

Beschreibung

Allgemeine Beschreibung

Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin 1 is also Involved in tumorigenesis by regulating apoptosis.

Physikalische Form

Lyophilized from PBS with trehalose and Brij35.

Rekonstituierung

Reconstitute with 100 μL deionized water.

Sonstige Hinweise

Human netrin-1 (aa 25-604) is fused at the C-terminus to the Fc portion of human IgG1.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable