SRP6320

FGF-12 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(e): FGF12B, FHF1, Fibroblast growth factor 12
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥90% (SDS-PAGE)
• Form: liquid
• Mol-Gew.: 22.6 kDa (201 aa, 1-181 aa + His Tag)
• Verpackung: pkg of 50 μg
• Konzentration: 1 mg/mL
• UniProt-Hinterlegungsnummer: P61328
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... FGF12(2257)

Beschreibung

Allgemeine Beschreibung

FGF12 (Fibroblast growth factor 12) is a member of the FGF superfamily of molecules which currently stands at 22 members. The FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 binds to IB2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and also plays an important role in intracellular signaling and ion exchange. Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physikalische Form

1 mg/mL in 20 mM Tris pH 7.5, 10% glycerol, 1 mM DTT, 2 mM EDTA.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H319
• P-Sätze: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable