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SRP3253

Sigma-Aldrich

SDF-1 beta from rat

≥95%(SDS-PAGE & HPLC), recombinant, expressed in E. coli, lyophilized, suitable for cell culture

Synonym(e):

CXCL12, PBSF, Stromal-Cell Derived Factor-1

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.32

product name

SDF-1 beta from rat, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

Biologische Quelle

rat

Rekombinant

expressed in E. coli

Assay

≥95% (HPLC)
≥95% (SDS-PAGE)

Form

lyophilized

Wirksamkeit

100.0-200.0 ng/mL

Mol-Gew.

8.4 kDa

Verpackung

pkg of 10 μg

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

<0.1 EU/μg endotoxin, tested

Farbe

yellow-white

UniProt-Hinterlegungsnummer

Q9QZD1

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

rat ... CXCL12(24772)

Allgemeine Beschreibung

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1b is an 8.4 kDa protein containing 72 amino acid residues.

Biochem./physiol. Wirkung

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. Recombinant rat SDF-1b is an 8.4 kDa protein containing 72 amino acid residues.

Sequenz

KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM

Physikalische Form

Lyophilized with no additives.

Rekonstituierung

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

M D'Apuzzo et al.
European journal of immunology, 27(7), 1788-1793 (1997-07-01)
In the bone marrow, progenitor (pro-) and precursor (pre-) B cells depend on close contact with stromal cells for growth and maturation. Stromal cell-derived factor 1 (SDF-1), also known as pre-B cell growth-stimulating factor, is produced by bone marrow stromal
E Oberlin et al.
Nature, 382(6594), 833-835 (1996-08-29)
A putative chemokine receptor that we previously cloned and termed LESTR has recently been shown to function as a co-receptor (termed fusin) for lymphocyte-tropic HIV-1 strains. Cells expressing CD4 became permissive to infection with T-cell-line-adapted HIV-1 strains of the syncytium-inducing

Artikel

Injectable Hydrogels for Cell Delivery and Tissue Regeneration

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

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