SML3736

Hypoxia probe 2

95% (UPLC)

• Synonym(e): 5’-Methoxy-1’,2’-dimethyl-3-(1-((3-oxo-3H-phenoxazin-7-yl)oxy)ethyl)-1H-indole-4’,7’-dione
• Empirische Formel (Hill-System): C₂₅H₂₀N₂O₆
• Molekulargewicht: 444.44
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95% (UPLC)
• Form: powder
• Lagerbedingungen: protect from light
• Farbe: , Faint orange to red
• Löslichkeit: DMSO: 2 mg/mL, clear (Warmed)
• Versandbedingung: wet ice
• Lagertemp.: -10 to -25°C

Beschreibung

Biochem./physiol. Wirkung

Hypoxia probe 2 is a resorufin-based non-fluorescent hypoxia probe that undergoes cytochrome P450 reductase (PH51)-catalyzed reduction to yield the fluorescent reporter resorufin (ex 545 nm, em 582 nm) in conditions of 4% O2 and lower, allowing imaging hypoxia levels similar to those detected by pimonidazole without the use of antibodies. When employed together with Tokyo green-based hypoxia probe 4 (Tokyo green ex 480 nm, em 515 nm), the probe pair allows the simultaneous (two-color) imaging of different hypoxia levels in living cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable