SML3439

IXA4

98% (HPLC)

• Synonym(e): N-​Methyl-​N-​[2-​(4-​methylphenoxy)​ethyl]​-​4-​[(1-​oxo-​3-​phenoxypropyl)​amino]​-1H-​pyrazole-​1-​acetamide
• Empirische Formel (Hill-System): C₂₄H₂₈N₄O₄
• CAS-Nummer: 1185329-96-7
• Molekulargewicht: 436.50
• MDL-Nummer: MFCD13023943
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: O=C(CN1N=CC(NC(CCOC2=CC=CC=C2)=O)=C1)N(C)CCOC3=CC=C(C=C3)C

Beschreibung

Biochem./physiol. Wirkung

IXA4 is a nontoxic, potent and highly selective IRE1-XBP1s signaling activator that induce ER proteostasis remodeling. IXA4 reduced Aβ levels and prevents APP-associated mitochondrial dysfunction in CHO7PA2 cells expressing the V717F APP (APPV717F) mutant.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable