SML1101

Nedocromil sodium

≥98% (HPLC)

• Synonym(e): 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid sodium salt, Nedocromil disodium salt
• Empirische Formel (Hill-System): C₁₉H₁₅NO₇ · 2 Na
• CAS-Nummer: 69049-74-7
• Molekulargewicht: 415.30
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: , white to beige to brown
• Löslichkeit: H₂O: 20 mg/mL, clear
• Lagertemp.: 2-8°C
• InChI: 1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2
• InChIKey: JQEKDNLKIVGXAU-UHFFFAOYSA-L

Beschreibung

Biochem./physiol. Wirkung

Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug. Nedocromil inhibits the degranulation of mast cells, and prevents the activation of and mediator release from a variety of inflammatory cell types. Nedocromil inhibits release of histamine, leukotriene C4, and prostaglandin D2, but has no antihistamine, bronchodilator, or corticosteroid activity itself.

Nedocromil is considered to be more effective in treating asthma compared to a placebo.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable