SML0909

Nefopam -hydrochlorid

≥98% (HPLC)

• Synonym(e): 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride, 5-Methyl-1-phenyl-1,3,4,6-tetrahydro-5H-benz[f]-2,5-oxazocine hydrochloride
• Empirische Formel (Hill-System): C₁₇H₁₉NO · HCl
• CAS-Nummer: 23327-57-3
• Molekulargewicht: 289.80
• EG-Nummer: 245-585-5
• MDL-Nummer: MFCD00012750
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825616
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• mp (Schmelzpunkt): 260 °C (dec.) (lit.)
• Löslichkeit: H₂O: 5 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: Cl.CN1CCOC(c2ccccc2)c3ccccc3C1
• InChI: 1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H
• InChIKey: CNNVSINJDJNHQK-UHFFFAOYSA-N

Beschreibung

Anwendung

Nefopam hydrochloride has been used as a standard for the quantitative determination of tramadol by gas chromatography–mass spectrometry (GC/MS).

Biochem./physiol. Wirkung

Nefopam is a centrally-acting analgesic drug of the benzoxazocine chemical class. Nefopam is a non-opioid, but has a potentiating effect on morphine and other opioids. Its mechanism of action is not certain, but may involve its action as a dopamine/serotonin/norepinephrine reuptake inhibitor.

Nefopam is a centrally-acting non-opioid analgesic drug of the benzoxazocine chemical class.

Leistungsmerkmale und Vorteile

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Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331
• P-Sätze: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable