SML0246

Tirofiban hydrochloride monohydrate

≥98% (HPLC)

• Synonym(e): L 700462, MK 383, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
• Empirische Formel (Hill-System): C₂₂H₃₆N₂O₅S·HCl·H₂O
• CAS-Nummer: 150915-40-5
• Molekulargewicht: 495.07
• MDL-Nummer: MFCD07368623
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825256
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D -10 to -18° (c=1, MeOH)
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: DMSO: >12 mg/mL at warmed to 60 °C
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: OC([C@@H](NS(CCCC)(=O)=O)CC1=CC=C(C=C1)OCCCCC2CCNCC2)=O.Cl.O
• InChI: 1S/C22H36N2O5S.ClH.H2O/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18;;/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26);1H;1H2/t21-;;/m0../s1
• InChIKey: HWAAPJPFZPHHBC-FGJQBABTSA-N
• Angaben zum Gen: human ... ITGA2B(3674) , ITGB3(3690)

Beschreibung

Anwendung

Tirofiban hydrochloride monohydrate has been used as an αIIbβ3 integrin (glycoprotein IIb/IIIa) inhibitor for mouse induced pluripotent stem cell (iPSC) culture.

Biochem./physiol. Wirkung

Tirofiban hydrochloride is a potent non-peptide, glycoprotein IIb/IIIa inhibitor. Blocks platelet aggregation and thrombus formation.

Tirofiban might cause thrombocytopenia.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable