SMB00348

Ginsenosid K

≥96% (HPLC)

• Synonym(e): Protopanaxadiol-20-O-glucosid
• Empirische Formel (Hill-System): C₃₆H₆₂O₈
• CAS-Nummer: 39262-14-1
• Molekulargewicht: 622.87
• UNSPSC-Code: 12352205
• PubChem Substanz-ID: 329824968
• NACRES: NA.25

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥96% (HPLC)
• Form: powder
• Anwendung(en): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES String: CC(C)=CCC[C@](C1C2[C@H](O)CC3[C@@]([C@]2(C)CC1)(C)CCC4C(C)(C)[C@@H](O)CC[C@@]43C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
• InChI: 1S/C36H62O8/c1-20(2)10-9-14-36(8,44-31-30(42)29(41)28(40)23(19-37)43-31)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(39)32(3,4)24(33)12-17-34(25,35)6/h10,21-31,37-42H,9,11-19H2,1-8H3/t21?,22-,23-,24?,25?,26+,27?,28-,29+,30-,31+,33+,34-,35-,36+/m1/s1
• InChIKey: FVIZARNDLVOMSU-KJULZEBLSA-N

Beschreibung

Allgemeine Beschreibung

Ginsenoside Compound K is a tetracyclic dammarane-type triterpenoid saponin found in the roots of Panax ginseng. It is a major constituent in ginseng, which has been traditionally used to increase resistance to stress and aging.

Anwendung

• Combination of Electrochemistry and Mass Spectrometry to Study Nitric Oxide Metabolism and Its Modulation by Compound K in Breast Cancer Cells.: This research explores the interaction of Ginsenoside Compound K with nitric oxide metabolism in breast cancer cells, employing a combination of electrochemical techniques and mass spectrometry to elucidate the metabolic pathways and potential therapeutic effects of Compound K (Zhao et al., 2022).


• Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS.: This article investigates the gut microbiota-mediated biotransformation of Panax notoginseng saponins, including Compound K, detailing the complex interactions and metabolic profiles in a biological system, which could inform their therapeutic use and bioavailability (Chen et al., 2018).

Biochem./physiol. Wirkung

Ginsenoside compound K has many pharmacological properties that include anti-diabetic, anti-inflammatory, hepatoprotective, anti-allergic, and anti-carcinogenic effects. It also displays neuroprotective properties, in mice it has shown recovery from synaptic loss and memory impairment. Ginsenoside K can inhibit several gene expressions in human umbilical vein endothelial cells (HUVECs), resulting in the inhibition of migration and angiogenesis of endothelial cells.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable