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Merck

SMB00251

Sigma-Aldrich

Avenacoside A

≥95% (LC/MS-ELSD)

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About This Item

Empirische Formel (Hill-System):
C51H82O23
CAS-Nummer:
Molekulargewicht:
1063.18
UNSPSC-Code:
12352200
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

Form

solid

Anwendung(en)

metabolomics
vitamins, nutraceuticals, and natural products

Lagertemp.

−20°C

InChI

1S/C51H82O23/c1-20-31-27(73-51(20)13-12-48(3,74-51)19-65-44-38(61)36(59)33(56)28(16-52)68-44)15-26-24-7-6-22-14-23(8-10-49(22,4)25(24)9-11-50(26,31)5)67-47-43(72-46-40(63)37(60)34(57)29(17-53)69-46)41(64)42(30(18-54)70-47)71-45-39(62)35(58)32(55)21(2)66-45/h6,20-21,23-47,52-64H,7-19H2,1-5H3/t20-,21-,23-,24+,25-,26-,27-,28+,29+,30+,31-,32-,33+,34+,35+,36-,37-,38+,39+,40+,41-,42+,43+,44+,45-,46-,47+,48-,49-,50-,51-/m0/s1

InChIKey

AAJHVVLGKCKBSH-QTPGKRPGSA-N

Allgemeine Beschreibung

Avenacoside A is a natural product derived from a plant source and exclusively present in whole grain oat. Avenacoside A is glycosylated with a trisaccharide at C-3 and with a glucose unit at C-26 position.

Anwendung

Avenacoside A may have been used as a reference standard to identify the metabolite annotation in the leaves of various Avena sativa (oats) cultivars.

Biochem./physiol. Wirkung

Avenacoside A displays anti-proliferative effects by inhibiting the growth of human colon cancer cells.It also serves as an exposure biomarker that is considered for epidemiologic studies with respect to whole grain uptake.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Avenacosides: Metabolism, and potential use as exposure biomarkers of oat intake
Wang P, et al.
Molecular Nutrition And Food Research, 61(7), 1700196-1700196 (2017)
Myoungjae Kim et al.
Molecules (Basel, Switzerland), 24(21) (2019-10-28)
Pancreatic cancer (PC) is one of the most aggressive malignancies in the world. Gemcitabine (Gem), a nucleoside pyrimidine analogue, is a first-line chemotherapeutic drug for PC, but the tumor response rate of Gem is very low and resistance to Gem
Chanel J Pretorius et al.
Metabolites, 11(3) (2021-04-04)
The first step in crop introduction-or breeding programmes-requires cultivar identification and characterisation. Rapid identification methods would therefore greatly improve registration, breeding, seed, trade and inspection processes. Metabolomics has proven to be indispensable in interrogating cellular biochemistry and phenotyping. Furthermore, metabolic

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