SAB5702374

Anti-RPA70/RPA1 Antibody, clone 5R7S3, Rabbit Monoclonal

• Synonym(e): HSSB, MST075, REPA1, RF-A, RP-A, RPA70
• UNSPSC-Code: 12352203
• NACRES: NA.46
• Klon: 5R7S3, monoclonal
• application: ChIP; IP; WB
• Speziesreaktivität: human, rat
• Methode(n): ChIP: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Materialien: colorless
• Klon: 5R7S3, monoclonal
• Form: liquid
• Mol-Gew.: 70 kDa
• Speziesreaktivität: human, rat
• Konzentration: 0.55 mg/mL
• Methode(n): ChIP: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• Farbe: colorless
• Isotyp: IgG
• Immunogene Sequenz: MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELE
• UniProt-Hinterlegungsnummer: P27694
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... RPA1(6117)

Beschreibung

Allgemeine Beschreibung

As part of the heterotrimeric replication protein A complex (RPA/RP-A, binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RPA70/RPA1 (P27694).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Anwendung

WB, IP, ChIP

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1