SAB5702281

Anti-Osteocalcin (BGLAP) Antibody, clone 2T1J7, Rabbit Monoclonal

• Synonym(e): BGLAP,BGP,OC,OCN,osteocalcin
• UNSPSC-Code: 12352203
• NACRES: NA.46

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Materialien: colorless
• Klon: 2T1J7, monoclonal
• Form: liquid
• Mol-Gew.: 11 kDa
• Speziesreaktivität: human, rat, rat
• Konzentration: 1 mg/mL
• Methode(n): western blot: 1:500 - 1:1000
• Farbe: colorless
• Isotyp: IgG
• UniProt-Hinterlegungsnummer: P02818
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... BGLAP(632)

Beschreibung

Allgemeine Beschreibung

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Recombinant protein of Human BGLAP.

Anwendung

WB

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H317,H411
• P-Sätze: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Gefahreneinstufungen: Aquatic Chronic 2 - Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3