SAB5700432

Anti-Phospho-IκBα-S32/36 antibody produced in rabbit

• Synonym(e): EDAID2, IKB alpha, IKBA, MAD-3, NFKBI, NFKBIA
• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 35
• Speziesreaktivität: human, mouse
• Konzentration: 0.54 mg/ml
• Methode(n): western blot: 1:500-1:1000
• UniProt-Hinterlegungsnummer: P25963
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer32/pSer36)
• Angaben zum Gen: human ... NFKBIA(4792)

Beschreibung

Allgemeine Beschreibung

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Immunogen

A synthetic phosphorylated peptide around S32 & S36 of human IκBα (NP_065390.1).

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable