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SAB5200006

Sigma-Aldrich

Monoclonal Anti-CRYAA antibody produced in mouse

clone 1H3.B8, 1 mg/mL, purified immunoglobulin

Synonym(e):

Anti-Acry1, Anti-Alpha A Crystallin, Anti-CRYA1, Anti-CRYAA, Anti-Heat Shock protein beta4, Anti-HspB4

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

1H3.B8, monoclonal

Form

buffered aqueous glycerol solution

Mol-Gew.

antigen predicted mol wt 20 kDa

Speziesreaktivität

bovine, rat, mouse, human

Konzentration

1 mg/mL

Methode(n)

indirect ELISA: suitable
western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NP_000385.1

UniProt-Hinterlegungsnummer

P02489

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CRYAA(1409)

Spezifität

Detects α-crystallin at ~20 kDa. Does not cross-react with αB-crystallin, βL-crystallin, βH- crystallin, γ-crystallin, Hsp25, Hsp27 or Hsp47 proteins.

Immunogen

Native Alpha Crystallin

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in PBS, pH 7.2, in 50% glycerol, and 0.09% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Shiwani Sharma et al.
Molecular vision, 24, 801-817 (2019-02-05)
Pseudoexfoliation (PEX) syndrome is an age-related progressive disease of the extracellular matrix with ocular manifestations. PEX is clinically diagnosed by the presence of extracellular exfoliative deposits on the anterior surface of the ocular lens. PEX syndrome is a major risk
Xiang-Jia Zhu et al.
Journal of cellular and molecular medicine, 22(2), 1118-1126 (2017-10-11)
Post-translational modifications in lens proteins are key causal factors in cataract. As the most abundant post-translational modification in the lens, racemization may be closely related to the pathogenesis of cataract. Racemization of αA-crystallin, a crucial structural and heat shock protein
Andrea Schlotterer et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4141-4153 (2018-11-30)
The aim of this study was to evaluate whether damage to the neurovascular unit in diabetes depends on reactive metabolites such as methylglyoxal (MG), and to assess its impact on retinal gene expression. Male Wistar rats were supplied with MG
Jason Tchieu et al.
Cell stem cell, 21(3), 399-410 (2017-09-09)
Directing the fate of human pluripotent stem cells (hPSCs) into different lineages requires variable starting conditions and components with undefined activities, introducing inconsistencies that confound reproducibility and assessment of specific perturbations. Here we introduce a simple, modular protocol for deriving

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