SAB4700232
Monoclonal Anti-CD81 antibody produced in mouse
clone M38, purified immunoglobulin, buffered aqueous solution
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About This Item
UNSPSC-Code:
12352203
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
mouse
Konjugat
unconjugated
Antikörperform
purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
M38, monoclonal
Form
buffered aqueous solution
Speziesreaktivität
rabbit, human, feline
Konzentration
1 mg/mL
Methode(n)
flow cytometry: suitable
Isotyp
IgG1
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Lagertemp.
2-8°C
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... CD81(975)
Allgemeine Beschreibung
Cluster of differentiation 81 (CD81) is expressed on the oocyte surface. It consists of five large helical segments and belongs to the tetraspanin family. The gene encoding this protein is localized on human chromosome 11p15.5.
The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
Immunogen
MOLT-4 (human T-ALL cell line)
Anwendung
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Biochem./physiol. Wirkung
Cluster of differentiation 81 (CD81) has a role in membrane organization, cell-cell interactions, cellular fusion and protein trafficking. It is also involved in receptor clustering and signaling. CD81 is overexpressed in cancers.
Leistungsmerkmale und Vorteile
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physikalische Form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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A role for CD81 and hepatitis C virus in hepatoma mobility.
Viruses, 6, 1454-1472 (2014)
CD81 as a tumor target.
Vences-Catalan F
Biochemical Society Transactions, 45, 531-535 (2017)
Oligomerization of the Tetraspanin CD81 via the Flexibility of Its ?-Loop.
Schmidt TH
Biophysical Journal, 110, 2463-2474 (2016)
A microarray-based DNA methylation study of
glioblastoma multiforme
Martinez R
Epigenetics, 4, 255-264 (2009)
Marguerite K McDonald et al.
Pain, 155(8), 1527-1539 (2014-05-06)
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