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Merck

SAB4700189

Sigma-Aldrich

Monoclonal Anti-CD44-FITC antibody produced in rat

clone IM7, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Anti-Pgp-1

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.44
Konjugat:
FITC conjugate
application:
FACS
Klon:
IM7, monoclonal
Speziesreaktivität:
mouse, human, canine
citations:
2
Methode(n):
flow cytometry: suitable

Biologische Quelle

rat

Konjugat

FITC conjugate

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

IM7, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse, human, canine

Konzentration

0.5 mg/mL

Methode(n)

flow cytometry: suitable

Isotyp

IgG2b

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CD44(960)

Allgemeine Beschreibung

The rat monoclonal antibody IM7 reacts with CD44 antigen (Phagocyte glycoprotein 1), an 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes. The antibody reacts with all isoforms of mouse CD44.

Immunogen

Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1

Anwendung

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Die Dokumentenbibliothek aufrufen

Venkatesh L Hegde et al.
Journal of leukocyte biology, 84(1), 134-142 (2008-04-05)
CD44 is involved in several biological processes owing to its dual role as a cell adhesion and signaling molecule. In an allogeneic dendritic cell (DC)-T cell interaction model, we show here that CD44 gets clustered at the contact between T
Jiayan Guo et al.
Molecular medicine reports, 16(4), 4095-4100 (2017-07-22)
Minimally invasive aesthetic and cosmetic procedures have increased in popularity. Injectable dermal fillers provide soft tissue augmentation, improve facial rejuvenation and wrinkles, and correct tissue defects. To investigate the use of adipose‑derived stem cells integrated with a hyaluronic acid based
Guodong Xiao et al.
Oncotarget, 8(61), 103261-103273 (2017-12-22)
Stem-like cells in tumor group featured the major role in the chemotherapy resistance of breast cancer, and the reduction of stem-like cells helped to perish the tumor when receiving chemotherapy. Smaller stem cells number indicated better therapeutic effect in vitro

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