SAB4503912

Anti-phospho-ETS1 (pThr³⁸) antibody produced in rabbit

affinity isolated antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 50 kDa
• Speziesreaktivität: rat, human, mouse
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P14921
• UniProt-Hinterlegungsnummer: P14921
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pThr38)
• Angaben zum Gen: human ... ETS1(2113)

Beschreibung

Allgemeine Beschreibung

ETS1 (E26 transformation specific sequence 1) is a proto‐oncogene. It is a member of the family of ETS transcriptional factors. ETS1 is usually expressed in lymphoid cells. This gene is mapped to human chromosome 11q24.

Immunogen

The antiserum was produced against synthesized peptide derived from human ETS1 around the phosphorylation site of Thr38.

Immunogen Range: 11-60

Biochem./physiol. Wirkung

ETS1 (E26 transformation specific sequence 1) participates in Pol ι‐mediated progression of ESCC (esophageal squamous cell carcinoma). This gene controls cancer cell invasion, metastasis and EMT (epithelial to mesenchymal transition). ETS1 also plays important roles in the lymphocyte development, function, apoptosis and inflammation.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable