SAB4502713

Anti-SODIUM CHANNEL-PAN antibody produced in rabbit

affinity isolated antibody

• Synonym(e): CIN5, HH1, SCN5A, Sodium channel protein, cardiac muscle α-subunit
• MDL-Nummer: MFCD02097413
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 227 kDa
• Speziesreaktivität: mouse, human, rat
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P35498
• UniProt-Hinterlegungsnummer: Q99250
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SCN2A(6323)

Beschreibung

Allgemeine Beschreibung

Anti-SODIUM CHANNEL-PAN Antibody detects endogenous levels of total SODIUM CHANNEL-PAN protein.

The SCN5A (sodium channel protein type 5 subunit α) gene is mapped to human chromosome 3p22.2. The encoded protein is known to be localized to cardiac cells.

Immunogen

The antiserum was produced against synthesized peptide derived from human Sodium Channel.

Immunogen Range: 1466-1515

Biochem./physiol. Wirkung

SCN5A (sodium channel protein type 5 subunit α) is associated with the regulation of myocardial excitability as it conducts cardiac depolarization via inward Na⁺ current. Mutation in SCN5A causes retarded cardiac repolarization resulting in congenital long QT syndrome and also causes Brugada syndrome due to loss of gene function.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable