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Merck

SAB4501583

Sigma-Aldrich

Anti-Integrin β1 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

CD29, FNRB, Fibronectin receptor β subunit, ITB1, Integrin VLA-4 β subunit

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 88 kDa

Speziesreaktivität

human, rat, mouse

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:1000
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... ITGB1(3688)

Allgemeine Beschreibung

Anti-Integrin β1 Antibody detects endogenous levels of total Integrin β1 protein.
Integrin β1 is a mechanosensor, that is located on human chromosome 10p11.22. It is present in normal cells and tumor-associated cells.

Immunogen

The antiserum was produced against synthesized peptide derived from human Integrin beta1.

Immunogen Range: 746-795

Anwendung

Anti-Integrin β1 antibody has been used in western blotting.

Biochem./physiol. Wirkung

Integrin β1 acts as an adhesive molecule in the development of de novo focal contact, keratinocyte migration and re-epithelialization of wound tissue.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

β1 Integrin as a Prognostic and Predictive Marker in Triple-Negative Breast Cancer.
Yin HL, et al.
International Journal of Molecular Sciences, 17(9) (2016)
Ggnbp2-Null Mutation in Mice Leads to Male Infertility due to a Defect at the Spermiogenesis Stage.
Liu L,et al.
The American Journal of Pathology, 187(11), 2508-2519 (2017)
Genomic aberrations associated with erlotinib resistance in non-small cell lung cancer cells.
Serizawa M, et al.
Anticancer Research, 33(12), 5223-5233 (2013)
β1 integrin signaling in asymmetric migration of keratinocytes under mechanical stretch in a co-cultured wound repair model.
Lu D, et al.
BioMedical Engineering OnLine, 15(2), 130-130 (2016)
Lingyun Liu et al.
The American journal of pathology, 187(11), 2508-2519 (2017-08-22)
Gametogenetin binding protein 2 (GGNBP2) is an evolutionarily conserved zinc finger protein. Although Ggnbp2-null embryos in the B6 background died because of a defective placenta, 6.8% of Ggnbp2-null mice in the B6/129 mixed background were viable and continued to adulthood.

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