SAB4500961

Anti-FLT3 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): CD135 antigen, STK-1, Stem cell tyrosine kinase 1, Tyrosine-protein kinase receptor FLT3
• MDL-Nummer: MFCD01864666
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 112 kDa
• Speziesreaktivität: mouse, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:1000; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P36888
• UniProt-Hinterlegungsnummer: P36888
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... FLT3(2322)

Beschreibung

Allgemeine Beschreibung

Anti-FLT3 antibody detects endogenous levels of total FLT3 protein.

FLT3 (Fms-like tyrosine kinase) is a member of tyrosine kinase (RTK) family. It has an extracellular domain consisting of five immunoglobulin-like domains and an intracellular kinase domain interrupted by a kinase insert. It is located on human chromosome 13q12.

Immunogen

The antiserum was produced against synthesized peptide derived from human FLT3.

Immunogen Range: 565-614

Biochem./physiol. Wirkung

Mutation in FLT3 (Fms-like tyrosine kinase) results in acute myeloid leukemia and it also induces warburg effect and offers therapeutic sensitivity to glycolytic inhibition.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable