SAB4300438

Anti-ZAP70 (Ab-493) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-FLJ17670 antibody produced in rabbit, Anti-FLJ17679 antibody produced in rabbit, Anti-SRK antibody produced in rabbit, Anti-STD antibody produced in rabbit, Anti-zeta-chain (TCR) associated protein kinase 70kDa antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~70 kDa
• Speziesreaktivität: rat, mouse, human
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• Isotyp: IgG
• Immunogene Sequenz: (S-Y-Y-T-A)
• NCBI-Hinterlegungsnummer: NP_001070.2
• UniProt-Hinterlegungsnummer: P43403
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ZAP70(7535)

Beschreibung

Immunogen

Peptide sequence around aa. 491-495 (S-Y-Y-T-A), according to the protein ZAP70.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the zeta chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-zeta chain, which can mediate the transduction of extracellular stimuli into cellular effector functions.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable