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SAB4300198

Sigma-Aldrich

Anti-phospho-MAPK9 (pThr183) antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-JNK-55 antibody produced in rabbit, Anti-JNK2 antibody produced in rabbit, Anti-JNK2A antibody produced in rabbit, Anti-JNK2ALPHA antibody produced in rabbit, Anti-mitogen-activated protein kinase 9 antibody produced in rabbit

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About This Item

MDL-Nummer:
MFCD02264074
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

~46 kDa
 ~54 kDa

Speziesreaktivität

rat, human, mouse

Konzentration

1 mg/mL

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

Isotyp

IgG

Immunogene Sequenz

(M-M-TP-P-Y)

NCBI-Hinterlegungsnummer

NP_001128516.1

UniProt-Hinterlegungsnummer

P45984

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pThr183)

Angaben zum Gen

human ... MAPK9(5601)

Verwandte Kategorien

Immunogen

Peptide sequence around phosphorylation site of threonine 183 (M-M-T(p)-P-Y), according to the protein MAPK9.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Kenta Niimi et al.
Biochemical and biophysical research communications, 489(4), 413-419 (2017-06-01)
Sprouting migration of lymphatic endothelial cell (LEC) is a pivotal step in lymphangiogenic process. However, its molecular mechanism remains unclear including effective migratory attractants. Meanwhile, forkhead transcription factor FOXO1 highly expresses in LEC nuclei, but its significance in LEC migratory
Manabu Inoue et al.
Scientific reports, 8(1), 6736-6736 (2018-05-02)
Immune responses to parasitic pathogens are affected by the host physiological condition. High-density lipoprotein (HDL) and low-density lipoprotein (LDL) are transporters of lipids between the liver and peripheral tissues, and modulate pro-inflammatory immune responses. Pathogenic mycobacteria are parasitic intracellular bacteria
Meraj A Khan et al.
Scientific reports, 7(1), 3409-3409 (2017-06-15)
Neutrophils cast neutrophil extracellular traps (NETs) to ensnare microbial pathogens. Nevertheless, the molecular rheostats that regulate NETosis in response to bacteria are not clearly established. We hypothesized that stress-activated protein kinase or c-Jun N-terminal Kinase (SAPK/JNK) is a molecular switch
Lilian Quero et al.
Arthritis research & therapy, 19(1), 245-245 (2017-11-04)
Toll-like receptors (TLRs) and macrophages play an important role in rheumatoid arthritis (RA). Currently, it is not clear whether inflammatory M1 or anti-inflammatory M2 predominate among the resident macrophages in the synovium. In the present study, we set out to
Lai Jiang et al.
Journal of neuroinflammation, 14(1), 174-174 (2017-09-02)
Activated astrocytes release matrix metalloproteinase-2/9 (MMP-2/9) to induce central sensitization and maintain neuropathic pain. However, the mechanisms involved in the activation of MMP-2/9 on astrocytes during pain remain poorly understood. Meanwhile, there is a lack of effective treatment to inhibit
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