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SAB3500370

Sigma-Aldrich

Anti-TRBP1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-TAR RNA binding protein 1, Anti-TARBP1, Anti-TRP-1, Anti-TRP-185

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About This Item

MDL-Nummer:
MFCD03097340
UNSPSC-Code:
12352203
NACRES:
NA.41
Konjugat:
unconjugated
application:
ELISA (i)
WB
Klon:
polyclonal
Speziesreaktivität:
human, mouse
citations:
4
Methode(n):
indirect ELISA: suitable
western blot: suitable

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human, mouse

Methode(n)

indirect ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

NP_005637

UniProt-Hinterlegungsnummer

Q13395

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TARBP1(6894)

Allgemeine Beschreibung

The gene TARBP1 (TAR (HIV-1) RNA binding protein 1) is mapped to human chromosome 1q42.2. The protein has dsRBDs (double stranded RNA binding domains), a KR motif in the dsRBD2 and a Medipal domain.

Immunogen

TRBP1 antibody was raised against a 17 amino acid peptide from near the center of human TRBP1.

Biochem./physiol. Wirkung

TARBP1 (TAR (HIV-1) RNA binding protein 1) binds strongly to the small hairpin trans-activation responsive (TAR) RNA of HIV (human immunodeficiency virus)-1. It might have a role in disengaging RNA polymerase II from HIV-1 TAR RNA. In addition, it is also a part of the RNA-induced silencing complex (RISC). It interacts with Dicer and helps in processing of pre-microRNAs. TARBP1 also participates in other cellular functions, such as protein synthesis, RNA post-translational modifications, cellular proliferation, gene expression and stress-associated cellular processes.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP3500370.

Physikalische Form

Supplied in PBS with 0.02% sodium azide.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
40110604

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Die Dokumentenbibliothek aufrufen

Robert D Beech et al.
Alcoholism, clinical and experimental research, 38(11), 2743-2753 (2014-11-26)
Alterations in stress-related gene expression may play a role in stress-related drinking and the risk of alcohol dependence. Microarrays were used to measure changes in gene expression in peripheral blood in nonsmoking, social drinking subjects exposed to 3 types of
Orla M Keane et al.
BMC genomics, 7, 42-42 (2006-03-07)
Gastrointestinal nematodes constitute a major cause of morbidity and mortality in grazing ruminants. Individual animals or breeds, however, are known to differ in their resistance to infection. Gene expression profiling allows us to examine large numbers of transcripts simultaneously in
F Wu-Baer et al.
The EMBO journal, 14(23), 5995-6009 (1995-12-01)
Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element located downstream of the transcription initiation site known as TAR. To characterize cellular factors that bind to TAR RNA and are involved in the
Sandrine Cornaz-Buros et al.
Cancer research, 74(22), 6610-6622 (2014-09-28)
Plasticity in cancer stem-like cells (CSC) may provide a key basis for cancer heterogeneity and therapeutic response. In this study, we assessed the effect of combining a drug that abrogates CSC properties with standard-of-care therapy in a Ewing sarcoma family

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