SAB2900692

Anti-NTSR1 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): NT-1r, NT1 receptor, NTR, NTS1, NTSR1, Neurotensin receptor type 1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): immunohistochemistry: 6 μg/mL
• UniProt-Hinterlegungsnummer: P30989
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... NTSR1(4923)

Beschreibung

Allgemeine Beschreibung

The neurotensin receptor 1 (NTSR1) gene has 4 exons and 3 introns and is 53.93 Kb long. NTSR1 is a member of the G protein-coupled receptor (GPCR) family. It consists of 4 extracellular and intracellular loops. It is expressed in the amygdal nucleus, ventral tegmental area, substantia nigra, striatum and entorhinal, and prefrontal cortices of the central nervous system.

Immunogen

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human NTSR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Elephant (94%); Marmoset (89%); Hamster (83%).

Anwendung

Anti-NTSR1 antibody produced in rabbit has been used in immunohistochemistry (IHC) (1:500).

Biochem./physiol. Wirkung

The neurotensin receptor 1 (NTSR1) plays a regulatory role in the initiation, proliferation, apoptosis, metastasis, and differentiation of tumors through several pathways. Overexpression of NTSR1 is seen in lung cancer, malignant prostatic tumors, and malignant cell lines. NTSR1 is a risk factor that participates in the progression of ductal breast cancer.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

Supplied at 1 mg/ml

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable