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Key Documents

Ursprungszeugnis (CoO)/Analysenzertifikate (CoA)

SAB2500278

Anti-CSNK1E antibody produced in goat

Name: Anti-CSNK1E antibody produced in goat
Brand: SIGMA

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-Casein kinase 1, Anti-HCKIE, Anti-MGC10398, Anti-RP1-5O6.1

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About This Item

UNSPSC-Code:

12352203

NACRES:

NA.41

Biologische Quelle

goat

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

rat, human, mouse, canine

Methode(n)

indirect ELISA: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

P49674

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CSNK1E(1454)

Allgemeine Beschreibung

Casein kinase 1 ε (CSNK1E) is part of the serine/threonine protein kinase family. The gene encoding it is localized on human chromosome 22q13.1.

Immunogen

Peptide with sequence C-PASQTSVPFDHLGK from the C Terminus of the protein sequence according to NP_001885.1; NP_689407.1.

Biochem./physiol. Wirkung

Casein kinase 1 ε (CSNK1E) phosphorylates proteins of the Wnt signaling cascade. It modulates tumor growth and cell division in salivary gland cancer, pancreatic and colon adenocarcinoma cells. CSNK1E phosphorylates dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32) and modulates dopamine receptor signaling. It also interacts with proteins involved in circadian rhythm.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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Piktogramme

GHS07

Signalwort

Warning

H-Sätze

H315 - H319

P-Sätze

P305 + P351 + P338

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes.

Takahisa Kuga et al.

Scientific reports, 6, 26557-26557 (2016-05-26)

FAM83H is essential for the formation of dental enamel because a mutation in the FAM83H gene causes amelogenesis imperfecta (AI). We previously reported that the overexpression of FAM83H often occurs and disorganizes the keratin cytoskeleton in colorectal cancer cells. We

Identification of genes associated with tumorigenesis of meibomian cell carcinoma by microarray analysis.

Kumar A, et. al

Genomics, 90(5), 559-566 (2007)

Association between a casein kinase 1 e gene polymorphism and schizophrenia in a Chinese Han population.

Huang Y

Journal of Molecular Neuroscience, 47(3), 470-474 (2012)

Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants.

Levran O

Pharmacogenomics, 15(16), 2001-2009 (2014)