SAB2106808

Anti-NUDT16L1 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): TIRR, Tudor Interacting Repair Regulator
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 23 kDa
• Speziesreaktivität: mouse, dog, rat, human, bovine, guinea pig, rabbit
• Konzentration: 0.5 mg - 1 mg/mL
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NM_032349
• UniProt-Hinterlegungsnummer: Q9BRJ7
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... NUDT16L1(84309)

Beschreibung

Allgemeine Beschreibung

Nudix hydrolase 16 like 1 (NUDT16L1) protein belongs to a nucleoside diphosphate-linked moiety X (Nudix) hydrolases family. It is also known as TIRR (tudor interacting repair regulator), which specifically interacts with the ionizing radiation induced foci formation (IRIF) region of P53 binding protein 1 (53BP1). NUDT16L1 gene is located on human chromosome 16p13.3.

Immunogen

Synthetic peptide directed towards the middle region of human NUDT16L1

Biochem./physiol. Wirkung

Nudix hydrolase 16 like 1 (NUDT16L1) repairs double strand breaks by masking the histone methyl-lysine binding function of P53 binding protein 1 (53BP1). NUDT16L1 acts as an inhibitor of 53BP1.

Sequenz

Synthetic peptide located within the following region: LNRVLGLGLGCLRLTEADYLSSHLTEGPHRVVAHLYARQLTLEQLHAVEI

Physikalische Form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable