SAB1401449

Monoclonal Anti-HERC3 antibody produced in mouse

clone 3G7, ascites fluid

• Synonym(e): KIAA0032
• UNSPSC-Code: 12352203
• NACRES: NA.41
• Klon: 3G7, monoclonal
• application: ELISA (c); WB
• Speziesreaktivität: human
• Methode(n): capture ELISA: suitable; western blot: 1:500-1:1000

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: ascites fluid
• Antikörper-Produkttyp: primary antibodies
• Klon: 3G7, monoclonal
• Speziesreaktivität: human
• Methode(n): capture ELISA: suitable; western blot: 1:500-1:1000
• Isotyp: IgG1κ
• NCBI-Hinterlegungsnummer: NM_014606
• UniProt-Hinterlegungsnummer: Q15034
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... HERC3(8916)

Beschreibung

Allgemeine Beschreibung

HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM

Immunogen

HERC3 (NP_055421, 1 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWG

Physikalische Form

Clear solution

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable