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Merck

SAB1306277

Sigma-Aldrich

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(e):

BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein, Osteocalcin

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Antikörperform

IgG fraction of antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

10963 Da

Speziesreaktivität

human

Methode(n)

immunohistochemistry: 1:50-1:100
western blot: 1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... BGLAP(632)

Allgemeine Beschreibung

Bone γ-carboxyglutamate protein (BGLAP) or osteocalcin (OCN) is a non-collagenous bone matrix protein expressed by osteoblasts. It possesses a Gla (γ-carboxyglutamate) domain. The gene encoding OCN is localized on human chromosome 1q22.

Anwendung

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit has been used in western blotting and immnuohistochemistry.

Biochem./physiol. Wirkung

Bone γ-carboxyglutamate protein (BGLAP) regulates osteogenic differentiation of mesenchymal stromal cells. It has a role in bone turnover and mineralization. The protein also has a role in energy metabolism. BGLAP may act as a mediator between glucose metabolism and bone tissue.

Physikalische Form

Supplied in PBS with 0.09% (W/V) sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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