SAB1300678

Anti-KLF4 antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

• Synonym(e): Anti-EZF, Anti-GKLF, Anti-Kruppel-like factor 4
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: saturated ammonium sulfate (SAS) precipitated
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI-Hinterlegungsnummer: NP_004226.3
• UniProt-Hinterlegungsnummer: O43474
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... KLF4(9314)

Beschreibung

Allgemeine Beschreibung

Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.

Immunogen

KLF4 (NP_004226.3, )
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.

Biochem./physiol. Wirkung

Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.

Physikalische Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable