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S5187

Sigma-Aldrich

Monoclonal Anti-SNAP-25 antibody produced in mouse

clone SP12, purified immunoglobulin, buffered aqueous solution

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About This Item

MDL-Nummer:
MFCD00675279
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

SP12, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

pig, hamster, rat, human

Methode(n)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Isotyp

IgG1

UniProt-Hinterlegungsnummer

P60880

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SNAP25(6616)
rat ... Snap25(25012)

Immunogen

crude human synaptic precipitate.

Physikalische Form

Solution in phosphate buffered saline containing 0.1% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

Analysenzertifikate (COA)

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Katsusuke Hata et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(52), 14481-14493 (2007-12-28)
Characterization of neuromuscular junction formation and function in mice lacking all neural cell adhesion molecule (NCAM) isoforms or only the 180 isoform demonstrated that the 180 isoform was required at adult synapses to maintain effective transmission with repetitive stimulation whereas
Rosane Aparecida Ribeiro et al.
Experimental physiology, 97(9), 1065-1073 (2012-05-01)
Ageing is associated with an increased impairment in glucose homeostasis and an increased incidence of type 2 diabetes. In this study, we evaluated β-cell function and its implications for glucose homeostasis in 24-month-old female Wistar rats. Aged rats showed lower plasma
S M Kolk et al.
Journal of neuroendocrinology, 12(7), 694-706 (2000-06-10)
In mammals, the synaptosomal-associated protein of 25 kDa, SNAP-25, is generally thought to play a role in synaptic exocytosis of neuronal messengers. Using a polyclonal antiserum against rat SNAP-25, we have shown the presence of a SNAP-25-like protein in the
Keita Takeuchi et al.
Brain research, 1373, 17-24 (2010-12-21)
We show here the expression, permeability and pharmacology of a voltage-gated channel in certain taste bud cells (TBCs) which is known to be permeable to Lucifer Yellow CH (LY) and known to release ATP as a neurotransmitter in response to
Satoshi Asano et al.
Biology open, 3(6), 463-474 (2014-05-09)
We previously reported that phospholipase C-related catalytically inactive protein (PRIP)-knockout mice exhibited hyperinsulinemia. Here, we investigated the role of PRIP in insulin granule exocytosis using Prip-knockdown mouse insulinoma (MIN6) cells. Insulin release from Prip-knockdown MIN6 cells was higher than that
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