S3572

Stevioside

from Stevia sp., ≥98% (HPLC), powder, p-aminohippurate transepithelial transport inhibitor

• Synonym(e): (4α-13-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid β-D-glucopyranosyl ester
• Empirische Formel (Hill-System): C₃₈H₆₀O₁₈ · xH₂O
• CAS-Nummer: 57817-89-7
• Molekulargewicht: 804.87 (anhydrous basis)
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329824534
• NACRES: NA.77

Eigenschaften

• Produktbezeichnung: Stevioside, ≥98% (HPLC)
• Biologische Quelle: Stevia sp.
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white
• Löslichkeit: DMSO: 25 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: O.C[C@@]12CCC[C@](C)(C1CC[C@]34CC(=C)[C@](CCC23)(C4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O
• InChI: 1S/C38H60O18.H2O/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-29(49)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-30(27(47)24(44)19(14-41)53-33)54-31-28(48)25(45)22(42)17(12-39)51-31;/h17-33,39-49H,1,4-15H2,2-3H3;1H2/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32+,33+,35-,36-,37-,38+;/m1./s1
• InChIKey: FVECWZKNZGXJJO-QMYNVHDOSA-N

Beschreibung

Anwendung

Stevioside hydrate has been used as a standard in high performance liquid chromatography (HPLC) for quantification of steviol glycosides.

Stevioside-induced ROS-mediated apoptosis was studied in human breast cancer cells.

Biochem./physiol. Wirkung

Stevioside hydrate is a diterpene glycoside present in Stevia sp.

Stevioside is a noncaloric natural sweetener, 300 times more potent than sucrose. It inhibits transepithelial transport of p-aminohippurate (PAH) by interfering with the organic anion transport system. At 0.5-1 mM, it showed no interaction with any organic anion transporters (OAT).

Stevioside reportedly has genotoxic effects in cultured mammalian cells.

Angaben zur Herstellung

Stevioside solutions should be prepared in DMSO. Highly pure stevioside has very poor water solubility.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves