RAB1708

Human SMPD1 ELISA

for serum, plasma and cell culture supernatants

• UNSPSC-Code: 41116158
• NACRES: NA.32

Eigenschaften

• Speziesreaktivität: human
• Methode(n): ELISA: suitable
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• Versandbedingung: wet ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Sphingomyelin phosphodiesterase-1 (SMPD1) gene encodes for acid sphingomyelinase (aSMase), which is involved in the hydrolysis of sphingomyelin to ceramides and phosphorylcholine in the late endosomes and lysosomes. Ceramides act as proinflammatory and proapoptotic second messengers. Mutations in the SMPD1 gene are associated with a lack of aSMase, leading to Niemann-Pick disease type A and B. The SMPD1 gene is mapped to the human chromosome at 11p15.1–11p15.4.

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Sonstige Hinweise

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Warning
• H-Sätze: H290
• P-Sätze: P234 - P390
• Gefahreneinstufungen: Met. Corr. 1
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable