Direkt zum Inhalt
Merck
Alle Fotos(1)

Key Documents

RAB1284

Sigma-Aldrich

Human BAMBI ELISA

for serum, plasma and cell culture supernatants

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human

Methode(n)

ELISA: suitable

Aufnahme

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... BAMBI(25805)

Allgemeine Beschreibung

BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) gene codes for a transmembrane glycoprotein which is a pseudo receptor belonging to the family of TGF-β (transforming growth factor β receptor) type I receptors. BAMBI is predominantly expressed in placenta, spleen and kidney medulla and also found liver, prostate, gut and kidney cortex.
This ELISA antibody pair detects Human BAMBI. Other species not yet determined.

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem./physiol. Wirkung

BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) acts as an inhibitor of TGF-β (transforming growth factor β receptor) signalling which causes epithelial-mesenchymal transition. Upregulation of BAMBI gene is observed in chronic obstructive pulmonary disease and a number of cancer including thyroid, liver, colorectal cancer and ovarian cancer. BAMBI might regulate the events of inflammation and remodeling processes.

Sonstige Hinweise

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Piktogramme

Corrosion
GHS05

Signalwort

Warning

H-Sätze

H290

P-Sätze

P234 - P390

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Downregulation of the TGFβ Pseudoreceptor BAMBI in Non?Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.
Marwitz S, et al.
Cancer Research (2016)
Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia
Jingping G, et al.
PLoS ONE, 10(8), e0134878-e0134878 (2015)
LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia
Yao H, et al.
Scientific Reports, 6, 27051-27051 (2016)
Kai Liu et al.
Molecular medicine reports, 10(2), 874-880 (2014-06-11)
The upregulation of bone morphogenetic protein and activin membrane‑bound inhibitor (BAMBI) has been observed in several types of malignant cancer, including thyroid, ovarian, liver and colorectal cancer. However, the pathological role and the regulatory mechanism of BAMBI in gastric cancer

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.