RAB0687
Human IL1F7 / Interleukin-37 ELISA Kit
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About This Item
Speziesreaktivität
human
Verpackung
kit of 96 wells (12 strips x 8 wells)
Methode(n)
ELISA: suitable
Aufnahme
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 81.92-20000 pg/mL
Nachweisverfahren
colorimetric
Versandbedingung
wet ice
Lagertemp.
−20°C
Angaben zum Gen
human ... IL1F7(27178)
Allgemeine Beschreibung
The IL1F7 ELISA kit provides for the quantitative measurement of IL-37 in cell culture supernatants, plasma and serum.
The interleukin 37 (IL1F7) gene is expressed in several tissues such as thymus, lymph nodes, testis, uterus, placenta, bone marrow and lungs. The gene IL1F7 exists in five isoforms IL1F7a-e. The IL1F7 gene is mapped to human chromosome 2q14.1.
The interleukin 37 (IL1F7) gene is expressed in several tissues such as thymus, lymph nodes, testis, uterus, placenta, bone marrow and lungs. The gene IL1F7 exists in five isoforms IL1F7a-e. The IL1F7 gene is mapped to human chromosome 2q14.1.
Anwendung
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem./physiol. Wirkung
Interleukin 37 (IL1F7) suppresses the innate immune response. The IL1F7 gene expression is associated with many inflammatory disorders including dermatosis, hepatopathy, digestive system disorders, autoimmune diseases, ischemia/reperfusion injury and other metabolic diseases. The anti-inflammatory action of IL1F7 might affect tumor inflammation mechanism.
Sonstige Hinweise
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Signalwort
Warning
H-Sätze
P-Sätze
Gefahreneinstufungen
Met. Corr. 1
Lagerklassenschlüssel
8A - Combustible corrosive hazardous materials
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Associations of the Interleukin?1 Gene Locus Polymorphisms with Risk to Hip and Knee Osteoarthritis: Gender and Subpopulation Differences.
Human immunology, 77(2), 151-161 (2013)
Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma.
Scientific Reports, 6, 26757-26757 (2016)
Frontiers in immunology, 9, 2351-2351 (2018-10-30)
Introduction: B-cell activation is pivotal in rheumatoid arthritis (RA) pathogenesis and represents a relevant therapeutic target. The main aim of this study was to characterize the profiles of B-cell factors and their decoy receptors in RA and evaluate their clinical
The effects of selective hematopoietic expression of human IL-37 on systemic inflammation and atherosclerosis in LDLr-deficient mice.
International Journal of Molecular Sciences, 18(8), 1672-1672 (2017)
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