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RAB0204

Sigma-Aldrich

Human GDF-15 / MIC-1  ELISA Kit

for serum, plasma, cell culture supernatant and urine

Synonym(e):

GDF-15, Growth/differentiation factor 15 , MIC-1, Macrophage inhibitory cytokine 1

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About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable
capture ELISA: suitable

Aufnahme

sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 1.1-800 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... GDF15(9518)

Allgemeine Beschreibung

Human GDF-15 / MIC-1 ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of a target protein in biological samples, such as serum, plasma, cell culture supernatants, urine and/or cell and tissue lysates. Growth differentiation factor-15 (GDF-15) is a cytokine for stress-response. It elevates during an inflammatory response and tissue injury. GDF-15 is also associated with cardiometabolic risk. It is localized in the adipocytes, macrophages, cardiomyocytes and vascular smooth muscle cells.

Immunogen

Recombinant Human GDF15

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human GDF-15 / MIC-1ELISA (enzyme-linked immunosorbent assay) kit has been used in the quantification of circulating macrophage inhibitory cytokine-1 (MIC-1) in venous blood samples.

Sonstige Hinweise

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB
  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDB
  • RABSTOP3ELISA Stop Solution (Item I)SDB
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB
  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion
GHS05

Signalwort

Warning

H-Sätze

H290

P-Sätze

P234 - P390

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Increased expression of GDF-15 may mediate ICU-acquired weakness by down-regulating muscle microRNAs.
Bloch SA
Thorax, 70(3), 219-228 (2015)
Hilde Engerud et al.
PloS one, 14(1), e0210585-e0210585 (2019-01-16)
Better biomarkers are needed in order to identify patients with endometrial carcinoma at risk of recurrence and who may profit from a more aggressive treatment regimen. Our objective was to explore the applicability of plasma growth differentiation factor 15 (GDF-15)
Azza Abdel Gawad Tantawy et al.
Blood cells, molecules & diseases, 53(4), 189-193 (2014-07-30)
High expression of growth differentiation factor-15 (GDF-15) contributes to pathological iron overload in thalassemia. Sickle cell syndromes are characterized by increased levels of erythropoiesis, although the primary defect involves the destruction of mature erythrocytes. To determine serum GDF-15 in 35
Sébastien Jeay et al.
Cancer research, 78(21), 6257-6267 (2018-08-24)
Activation of p53 by inhibitors of the p53-MDM2 interaction is being pursued as a therapeutic strategy in p53 wild-type cancers. Here, we report distinct mechanisms by which the novel, potent, and selective inhibitor of the p53-MDM2 interaction HDM201 elicits therapeutic
Insulin resistance, type 1 and type 2 diabetes, and related complications 2015
Ndisang J F, et al.
Journal of Diabetes Research (2015)
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