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Merck

RAB0200

Sigma-Aldrich

Gastrin EIA Kit

for serum, plasma, culture supernatant and cell lysates

Synonym(e):

Gastrin

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About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human, mouse, rat

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable
enzyme immunoassay: suitable

Aufnahme

sample type serum
sample type plasma
sample type culture supernatant(s)
sample type cell lysate

assay range

inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 9.92 pg/mL
standard curve range: 0.1–1000 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... GAST(2520)

Allgemeine Beschreibung

The Gastrin-I Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Gastrin-I peptide based on the principle of Competitive Enzyme Immunoassay.
Gastrin is a peptide hormone released in gastrointestinal region of the body. It is specifically produced by the G-cells in stomach and duodenum. During embryogenesis, gastrin secretion is observed only in the pancreas. Gastrin is also localized to the renal tubules. The GAST gene is mapped to human chromosome 17q21.2.

Immunogen

Gastrin, synthetic peptide

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Gastrin EIA Kit has been used to estimate the levels of gastrin hormone in plasma or serum sample.

Biochem./physiol. Wirkung

Gastrin is responsible for epithelial cell proliferation and differentiation. Gastrin regulates the action of parietal cells in secretion of gastric acid and growth factors essential for stomach maintenance. Gastrin maintains sodium ion homeostasis and controls body′s blood pressure. Hypoxial conditions in in vitro and in vivo analysis may elevate the expression of gastrin hormone in cancer cells in order to promote angiogenesis.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB

  • RABHRP3HRP-StreptavidinSDB

Piktogramme

Corrosion

Signalwort

Warning

H-Sätze

P-Sätze

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials


Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Genomic analysis reveals the molecular heterogeneity of ovarian clear cell carcinomas.
Tan D S, et al.
Clinical Cancer Research, 17(6), 1521-1534 (2011)
The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition.
Pierre J F, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 309(6), G431-G442 (2015)
Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions.
Laval M, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 308(2), G76-G84 (2014)
Pancreatic beta cells express the fetal islet hormone gastrin in rodent and human diabetes.
Dahan T, et al.
Diabetes (2016)
Gastrin induces parathyroid hormone-like hormone expression in gastric parietal cells.
Al Menhali A, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 312(6), G649-G657 (2017)

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