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Merck

PRS2301

Sigma-Aldrich

Anti-AIF antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-Connector enhancer of kinase suppressor of Ras 1

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

predicted mol wt 67 kDa

Speziesreaktivität

mouse, human, rat

Methode(n)

immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CNKSR1(10256)

Allgemeine Beschreibung

The previously assigned protein identifier O95381 has been merged into Q969H4. Full details can be found on the UniProt database.

Immunogen

a peptide corresponding to amino acids 593-606 of human AIF. This sequence is identical to mouse and rat AIF.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP2301.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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TASK-3 (KCNK9 or K2P9.1) channels are thought to promote proliferation and/or survival of malignantly transformed cells, most likely by increasing their hypoxia tolerance. Based on our previous results that suggested mitochondrial expression of TASK-3 channels, we hypothesized that TASK-3 channels
Shengqiang Xu et al.
PloS one, 9(7), e100824-e100824 (2014-07-06)
Apoptosis-inducing factor (AIF) plays a crucial role in caspase-independent programmed cell death by triggering chromatin condensation and DNA fragmentation. Therefore, it might be involved in cell homeostasis and tumor development. In this study, we report significant AIF downregulation in the

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