MAK551

Butyrylcholinesterase (BChE) Activity Assay Kit

sufficient for 100 colorimetric tests

• UNSPSC-Code: 41116104
• NACRES: NA.21

Eigenschaften

• Nachweisverfahren: colorimetric
• Relevante Krankheit(en): endocrinological disorders, diabetes; obesity; cardiovascular diseases
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Butyrylcholinesterase (EC 3.1.1.8; BChE), also known as pseudocholinesterase or plasma cholinesterase, is mainly synthesized in liver and present in blood. BChE is a nonspecific cholinesterase enzyme and can hydrolyze many different choline esters, serving as the first line of defense against toxic compounds reaching the bloodstream. ​

The Butyrylcholinesterase Activity Assay Kit is based on a synthetic butyrylthiocholine based substrate, which can be hydrolyzed by BChE and produce thiocholine. Thiocholine can react with 5, 5′-dithiobis (2-nitrobenzoic acid) (DTNB) and generates a yellow chromophore that can be detected at 410 nm. The assay is convenient, sensitive and can detect as low as 6 mU/mL in a variety of samples.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H334
• P-Sätze: P261 - P284 - P501
• Gefahreneinstufungen: Resp. Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3