M5815

Monoclonal Anti-Myogenin antibody produced in mouse

clone F12B, purified immunoglobulin, buffered aqueous solution

• MDL-Nummer: MFCD01322371
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: F12B, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 34 kDa
• Speziesreaktivität: mouse, rat, human
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1-2 μg/mL using rhabdomyosarcoma tissue sections; immunoprecipitation (IP): 2 μg using 1 mg protein lysate; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1 μg/mL
• Isotyp: IgG1
• UniProt-Hinterlegungsnummer: P15173
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... MYOG(4656) ; mouse ... Myog(17928) ; rat ... Myog(29148)

Beschreibung

Allgemeine Beschreibung

Myogenin belongs to the basic helix-loop-helix (bHLH) superfamily.

Myogenin is a transcription factor present in the nucleus. It possesses an amino-acid rich region and a helix-loop-helix structure. The gene encoding it is localized on human chromosome 1q31-41 and has three exons.

Immunogen

rat recombinant myogenin (amino acids 30-224).

Anwendung

Monoclonal Anti-Myogenin antibody produced in mouse has been used in immunohistochemistry, immunofluorescence and western blotting.

Biochem./physiol. Wirkung

Myogenin acts as a biomarker in rhabdomyosarcoma (RMS). It has a role in developmental processes, such as hematopoiesis, neurogenesis, myogenesis, tumor cell invasion and metastasis.

Myogenin acts as a regulator during myoblast and skeletal muscle differentiation. It is considered as a definite marker for skeletal muscle differentiation.

Physikalische Form

Solution in phosphate buffered saline containing 0.08% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable