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L3262

Sigma-Aldrich

Anti-Lactoferrin antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonym(e):

Anti-Draculin, Anti-Draculin-1

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About This Item

MDL-Nummer:
MFCD00162524
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

rabbit

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

fractionated antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

lyophilized powder

Speziesreaktivität

human

Verpackung

vial of 2 mL lyophilized antiserum

Methode(n)

direct ELISA: 1:10,000 using using human lactoferrin

UniProt-Hinterlegungsnummer

P02788

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... LTF(4057)

Allgemeine Beschreibung

Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.

Spezifität

Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.

Anwendung

Anti-Lactoferrin antibody produced in rabbit has been used in:
  • western blotting
  • indirect immunofluorescence
  • flow cytometry
  • enzyme-linked immunosorbent assay (ELISA)

Biochem./physiol. Wirkung

A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.

Physikalische Form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Rekonstituierung

Reconstitute with 2 ml deionized water.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Alan Grupioni Lourenço et al.
World journal of virology, 3(2), 11-17 (2014-07-16)
To study the effect of seminal plasma on Chemokine (C-C motif) ligand 20 (CCL20) production by epithelial cells and its relationship with lactoferrin. HEC-1A cells, a cell line derived from a monostratified endocervical epithelium, were incubated with samples of seminal
A novel murine anti-lactoferrin monoclonal antibody activates human polymorphonuclear leukocytes through membrane-bound lactoferrin and TLR4
Hu XM, et al.
BioMed Research International, 2015(2), 439-439 (2015)
Pamela L Beatty et al.
Cancer prevention research (Philadelphia, Pa.), 3(4), 438-446 (2010-03-25)
Association of chronic inflammation with an increased risk of cancer is well established, but the contributions of innate versus adaptive immunity are not fully delineated. There has furthermore been little consideration of the role played by chronic inflammation-associated antigens, including
Lulu Hu et al.
Scientific reports, 7(1), 4230-4230 (2017-06-28)
Lactoferrin (LTF), an important first line defense molecule against infection, is a common target for humoral autoimmune reactions in humans. Since LTF is a multifunctional protein capable of activating innate immune cells via various surface receptors, we hypothesized that LTF-containing
Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe
Hu L, et al.
Bioscience, Biotechnology, and Biochemistry, 80(2), 257-263 (2016)
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