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I7389

Interleukin-3 human

Name: Interleukin-3 human
Brand: SIGMA

IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(e):

hIL-3, IL-3

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About This Item

MDL-Nummer:

MFCD00147276

UNSPSC-Code:

12352202

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Sigma-Aldrich

I5879

3-Isobutyl-1-methylxanthin

Biologische Quelle

human

Qualitätsniveau

200

Rekombinant

expressed in E. coli

Assay

≥95% (SDS-PAGE)

Form

lyophilized powder

Wirksamkeit

<0.5 ng/mL ED₅₀

Qualität

endotoxin tested

Verpackung

pkg of 4 μg

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

<0.1 EU/μg

UniProt-Hinterlegungsnummer

P08700

Versandbedingung

dry ice

Lagertemp.

−20°C

Angaben zum Gen

human ... IL3(3562)

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Biochem./physiol. Wirkung

Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.

Einheitendefinition

One unit is the amount of IL-3 required to induce half-maximal incorportion of ³H thymidine. Activity also is expressed in Reference units (NIBSC reference preparation for IL-3 code 88/87).

Physikalische Form

Lyophilized from a 0.2 μm filtered solution.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

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