I2636
IgA aus human colostrum
reagent grade, buffered aqueous solution
Synonym(e):
Human-IgA
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About This Item
Empfohlene Produkte
Konjugat
unconjugated
Qualitätsniveau
Qualität
reagent grade
Form
buffered aqueous solution
Versandbedingung
dry ice
Lagertemp.
−20°C
Posttranslationale Modifikation Target
unmodified
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Allgemeine Beschreibung
Immunoglobulin A (IgA) is the most abundant antibody isotype produced in humans. IgAs are heterogeneous and exist astwo IgA subtypes. It has the ability to form multimers by interacting with the joining (J) chain. It is present in large quantities in blood. Immunoglobulin A (IgA) antibodies protect mucosal surfaces against invading pathogens.
Anwendung
IgA from human colostrum has been used to find out percent cross-selectivity values for lactoferrin immunosensors versus several common proteins contained in milk and saliva. It has also been used in western blotting.
IgA from human colostrum is a suitable ELISA standard used to estimate the concentrations of IgA in human B cell culture supernatants and in human blood, colostrum and cord blood samples.
Biochem./physiol. Wirkung
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces.
Physikalische Form
Solution in 0.01 M Tris-HCl, 0.1 M sodium chloride, pH 8.0, containing 15 mM sodium azide
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Katie L Edwards et al.
Conservation physiology, 7(1), coy077-coy077 (2019-03-25)
Additional measures of well-being would be beneficial to the management of a variety of species in human care, including elephants. Immunoglobulin A (IgA) is an immune protein associated with pathogen defense, which has been demonstrated to decrease during times of
Ekaterina N Gorshkova et al.
Pharmacology, 107(7-8), 341-350 (2021-12-06)
As has been shown previously, various protein-modifying agents can change the antigen-binding properties of immunoglobulins. However, induced polyspecificity of human secretory immunoglobulin A (sIgA) has not been previously characterized in detail. In the present study, human secretory immunoglobulin A (IgA)
Further development of lactoferrin immunosensor (part III)
Campanella L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 186-193 (2010)
Danielle E Baranova et al.
Pathogens & immunity, 5(1), 89-116 (2021-06-18)
In cholera epidemics, the spread of disease can easily outpace vaccine control measures. The advent of technologies enabling the expression of recombinant proteins, including antibodies, in the milk of transgenic animals raises the prospect of developing a self-administered and cost-effective
Sjm van Leeuwen et al.
Oral diseases, 24(6), 972-982 (2018-04-11)
One explorative observational study in two parts was performed to examine early salivary changes in relation to oral mucositis (OM) in multiple myeloma patients treated with high-dose melphalan and autologous haematopoietic stem cell transplantation (HSCT). As cryotherapy was introduced after
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