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Merck

H7403

Sigma-Aldrich

Anti-Histamine antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti Histamine Antibody, Histamine Antibody, Histamine Antibody - Anti-Histamine antibody produced in rabbit

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

wide range

Methode(n)

dot blot: 1:14,000 using histamine-BSA.
immunohistochemistry: 1:100 using 4% paraformaldehyde/4% carbodiimide-fixed or 4% paraformaldehyde-fixed sections of rat stomach

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

Histamine, (2-(4-Imidazolyl)ethylamine), is a widely distributed substance in peripheral tissues. Histamine is localized in mast cells, neuronal cells and neuroendocrine cells of the gastric tract. It is also expressed in lungs, kidney, in cerebrovascular endothelial cells and throughout the peripheral nervous system.

Spezifität

The product specifically stains histamine-containing cells in paraformaldehyde/carbodiimide-fixed or paraformaldehyde-fixed, paraffin-embedded sections of rat stomach (endocrine cells and mast cells).

Immunogen

histamine conjugated to succinylated KLH

Anwendung

Anti-Histamine antibody produced in rabbit has been used:
  • in immunohistochemistry
  • to test immunohistochemical reactions of Pseudophoxinus antalyae digestive system tissues
  • in immunocytochemical assays
  • in immunofluorescence assays

Biochem./physiol. Wirkung

Histamine, (2-(4-Imidazolyl)ethylamine) mediates a variety of physiological activities including inflammation, gastric acid secretion and smooth muscle contraction. It is also implicated in modulation of cell growth and differentiation, during embryogenesis, and tumor growth and in the suppression of mitogen-induced lymphocyte proliferation. In the central nervous system (CNS), histamine acts as a neurotransmitter/ neuromodulator of various brain activities.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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